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Temporomandibular joint dysfunction syndrome

MedGen UID:
21093
Concept ID:
C0039496
Disease or Syndrome
Synonyms: Costen Syndrome; Costen's Syndrome; Costens Syndrome; Joint Syndrome, Temporomandibular; Myofascial Pain Dysfunction Syndrome, Temporomandibular Joint; Syndrome, Costen's; Syndrome, Temporomandibular Joint; Syndrome, TMJ; Temporomandibular Joint Dysfunction Syndrome; Temporomandibular Joint Syndrome; TMJ Syndrome
SNOMED CT: Temporomandibular joint-pain-dysfunction syndrome (386207004); Costen's syndrome (386207004); Mandibular dysfunction (386207004); Costen's complex (386207004); Temporomandibular joint pain dysfunction syndrome (386207004); Snapping jaw (386207004); TMJPDS - temporomandibular joint pain dysfunction syndrome (386207004); TMJ (temporomandibular joint) syndrome (386207004); Temporomandibular joint syndrome (41888000)
 
Monarch Initiative: MONDO:0021895

Definition

A common disorder noted with jaw movement. It may be caused by malocclusion, repetitive use injury, trauma or arthritis. It is more prevalent among females between their second and fourth decades. Clinical signs include preauricular pain, temporomandibular joint clicking (as the mandibular condyle slips from the articulation made with the capsular disc and temporal bone) and restriction of jaw motion. Clinical course is typically benign but may progress to associated headaches, ear and neck pain, tinnitus and dislocation of temporomandibular joint. Prognosis is favorable as a majority of cases will respond to conservative management. [from NCI]

Term Hierarchy

CClinical test,  RResearch test,  OOMIM,  GGeneReviews,  VClinVar  
  • CROGVTemporomandibular joint dysfunction syndrome

Professional guidelines

PubMed

Durham J, Ohrbach R, Baad-Hansen L, Davies S, De Laat A, Goncalves DG, Gordan VV, Goulet JP, Häggman-Henrikson B, Horton M, Koutris M, Law A, List T, Lobbezoo F, Michelotti A, Nixdorf DR, Oyarzo JF, Peck C, Penlington C, Raphael KG, Santiago V, Sharma S, Svensson P, Visscher CM, Yoshiki I, Alstergren P; INfORM
J Oral Rehabil 2024 May;51(5):785-794. Epub 2023 Dec 27 doi: 10.1111/joor.13652. PMID: 38151896
Tran C, Ghahreman K, Huppa C, Gallagher JE
Int J Oral Maxillofac Surg 2022 Sep;51(9):1211-1225. Epub 2022 Mar 23 doi: 10.1016/j.ijom.2021.11.009. PMID: 35339331
Asquini G, Rushton A, Pitance L, Heneghan N, Falla D
Syst Rev 2021 Mar 8;10(1):70. doi: 10.1186/s13643-021-01623-7. PMID: 33685496Free PMC Article

Recent clinical studies

Etiology

Urbani G, Cozendey-Silva EN, Jesus LF
Cien Saude Colet 2019 May 30;24(5):1753-1765. doi: 10.1590/1413-81232018245.16162017. PMID: 31166510
Effat KG
J Laryngol Otol 2016 Dec;130(12):1137-1141. doi: 10.1017/S0022215116009300. PMID: 27938466
DuPont JS Jr, Brown CE
Cranio 2009 Jul;27(3):180-4. doi: 10.1179/crn.2009.027. PMID: 19697646
Wilkes CH
Arch Otolaryngol Head Neck Surg 1989 Apr;115(4):469-77. doi: 10.1001/archotol.1989.01860280067019. PMID: 2923691
Nel H
J Prosthet Dent 1978 Oct;40(4):438-41. doi: 10.1016/0022-3913(78)90129-4. PMID: 279694

Diagnosis

Lomas J, Gurgenci T, Jackson C, Campbell D
Aust J Gen Pract 2018 Apr;47(4):212-215. doi: 10.31128/AFP-10-17-4375. PMID: 29621862
Fernández-de-las-Penas C, Svensson P
Curr Rheumatol Rev 2016;12(1):40-54. doi: 10.2174/1573397112666151231110947. PMID: 26717949
Miernik M, Wieckiewicz M, Paradowska A, Wieckiewicz W
Adv Clin Exp Med 2012 Sep-Oct;21(5):681-5. PMID: 23356206
Solberg WK
Semin Neurol 1988 Dec;8(4):291-7. doi: 10.1055/s-2008-1041392. PMID: 3074424
Guralnick W, Kaban LB, Merrill RG
N Engl J Med 1978 Jul 20;299(3):123-9. doi: 10.1056/NEJM197807202990304. PMID: 661872

Therapy

Brandão RAFS, Mendes CMC, Brandão Filho RA, De Sena EP
Cranio 2022 May;40(3):199-206. Epub 2020 Jan 3 doi: 10.1080/08869634.2019.1708607. PMID: 31900091
Kaya DI, Ataoglu H
Niger J Clin Pract 2021 Mar;24(3):412-417. doi: 10.4103/njcp.njcp_251_20. PMID: 33723117
Craane B, Dijkstra PU, Stappaerts K, De Laat A
J Dent Res 2012 Apr;91(4):364-9. Epub 2012 Feb 8 doi: 10.1177/0022034512438275. PMID: 22318373
Epstein JB
J Am Dent Assoc 1984 Jul;109(1):71-4. doi: 10.14219/jada.archive.1984.0302. PMID: 6205032
Schärer P
Front Oral Physiol 1974;1(0):293-322. PMID: 4609874

Prognosis

Craane B, Dijkstra PU, Stappaerts K, De Laat A
J Dent Res 2012 Apr;91(4):364-9. Epub 2012 Feb 8 doi: 10.1177/0022034512438275. PMID: 22318373
Okeson JP
Tex Dent J 2000 Jul;117(7):64-74. PMID: 11858065
Okeson JP
Northwest Dent 2000 Sep-Oct;79(5):37-44. PMID: 11413614
Von Korff M, Ormel J, Keefe FJ, Dworkin SF
Pain 1992 Aug;50(2):133-149. doi: 10.1016/0304-3959(92)90154-4. PMID: 1408309
Wilkes CH
Arch Otolaryngol Head Neck Surg 1989 Apr;115(4):469-77. doi: 10.1001/archotol.1989.01860280067019. PMID: 2923691

Clinical prediction guides

Kaya DI, Ataoglu H
Niger J Clin Pract 2021 Mar;24(3):412-417. doi: 10.4103/njcp.njcp_251_20. PMID: 33723117
Braz MA, Freitas Portella F, Seehaber KA, Bavaresco CS, Rivaldo EG
J Oral Rehabil 2020 Apr;47(4):536-546. Epub 2020 Jan 16 doi: 10.1111/joor.12930. PMID: 31880832
Urbani G, Cozendey-Silva EN, Jesus LF
Cien Saude Colet 2019 May 30;24(5):1753-1765. doi: 10.1590/1413-81232018245.16162017. PMID: 31166510
Okeson JP
Tex Dent J 2000 Jul;117(7):64-74. PMID: 11858065
Wilkes CH
Arch Otolaryngol Head Neck Surg 1989 Apr;115(4):469-77. doi: 10.1001/archotol.1989.01860280067019. PMID: 2923691

Recent systematic reviews

Almășan O, Hedeșiu M, Băciuț M, Buduru S, Dinu C
J Oral Rehabil 2023 Mar;50(3):243-255. Epub 2023 Jan 12 doi: 10.1111/joor.13409. PMID: 36582136
Stepan L, Shaw CL, Oue S
J Laryngol Otol 2017 Jan;131(S1):S50-S56. Epub 2016 Oct 27 doi: 10.1017/S0022215116009191. PMID: 27786149
Fernández-de-las-Penas C, Svensson P
Curr Rheumatol Rev 2016;12(1):40-54. doi: 10.2174/1573397112666151231110947. PMID: 26717949
Rocha CP, Croci CS, Caria PH
J Oral Rehabil 2013 Nov;40(11):875-81. Epub 2013 Oct 7 doi: 10.1111/joor.12104. PMID: 24118029
de Freitas RF, Ferreira MÂ, Barbosa GA, Calderon PS
J Oral Rehabil 2013 Nov;40(11):864-74. Epub 2013 Sep 18 doi: 10.1111/joor.12098. PMID: 24102692

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